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	Provedor de dados BJMBR (1) Autor Aoki,M.S. (1) Miyabara,E.H. (1) Moriscot,A.S. (1) Salvini,T.F. (1) Soares,A.G. (1) Palavra-chave Calcineurin (1) Cyclosporin-A (1) Hypertrophy (1) Immobilization (1) Recovery (1) Skeletal muscle (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2006 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Cyclosporin-A does not affect skeletal muscle mass during disuse and recovery BJMBR Aoki,M.S.; Miyabara,E.H.; Soares,A.G.; Salvini,T.F.; Moriscot,A.S.. Cyclosporin-A (CsA) is an immunosuppressive drug that acts as an inhibitor of calcineurin, a calcium phosphatase that has been suggested to play a role in skeletal muscle hypertrophy. The aim of the present study was to determine the effect of CsA administration (25 mg kg-1 day-1) on skeletal muscle mass and phenotype during disuse and recovery. Male Wistar rats received vehicle (N = 8) or CsA (N = 8) during hind limb immobilization (N = 8) and recovery (N = 8). Muscle weight (dry/wet) and cross-sectional area were evaluated to verify the effect of CsA treatment on muscle mass. Muscle phenotype was assessed by histochemistry of myosin ATPase. CsA administration during immobilization and recovery did not change muscle/body weight ratio in the soleus (SOL)... Tipo: Info:eu-repo/semantics/article Palavras-chave: Calcineurin; Immobilization; Recovery; Skeletal muscle; Hypertrophy; Cyclosporin-A. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000200011 Registros recuperados: 1 Primeira ... 1 ... Última

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